Phenylboronic acid CAS 98-80-6: A Buyer’s Guide to Specifications, Applications, and Supplier Selection

22, Sep. 2026

 

Phenylboronic Acid CAS 98-80-6: A Buyer’s Guide to Specifications, Applications, and Supplier Selection

If you are sourcing Phenylboronic acid CAS 98-80-6, I recommend evaluating four areas first: chemical identity, required quality specification, intended application, and supplier reliability. Phenylboronic acid is an organoboron compound commonly used as a reagent and pharmaceutical intermediate, especially in palladium-catalyzed cross-coupling chemistry. Its molecular formula is C6H7BO2, and its molecular weight is 121.93 g/mol. At Maison Chemical, I support B2B buyers by matching material specifications, packaging, documentation, and supply plans to the actual needs of their project.

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Who This Guide Is For

I prepared this guide for procurement teams, pharmaceutical and fine chemical manufacturers, research organizations, distributors, and process development laboratories. It is especially useful when a buyer needs to compare suppliers beyond a simple catalog price. The right choice depends on whether you require research-grade material, production-scale quantities, repeat deliveries, or documentation suitable for internal quality review.

I also recommend using this information as a screening framework rather than as a substitute for your own analytical method, regulatory review, or process validation. Different applications may require different limits for assay, moisture, residual solvents, particle characteristics, and impurities. Before placing a commercial order, I encourage buyers to confirm the complete specification with the supplier.

What Is Phenylboronic Acid CAS 98-80-6?

Phenylboronic acid, identified by CAS Registry Number 98-80-6, is an aromatic boronic acid containing a phenyl group attached to a boronic acid functional group. It is commonly supplied as a white to off-white solid, although appearance can vary with manufacturing conditions, handling, and storage. The compound is valued because its boronic acid group can participate in carbon–carbon bond-forming reactions and reversible interactions with certain diol-containing compounds.

In practical purchasing, the CAS number confirms the target chemical identity, but it does not define the entire commercial specification. I therefore advise buyers to review the chemical name, molecular formula, molecular weight, assay method, appearance, impurity profile, water content, packaging, and storage recommendations together. This approach reduces the risk of selecting a product that has the correct CAS number but is unsuitable for the intended process.

Core Functions and Common Applications

Use in Cross-Coupling Chemistry

One of the best-known uses of Phenylboronic acid is as a coupling partner in Suzuki–Miyaura reactions. In suitable reaction systems, the phenyl group can be transferred to an organic electrophile, allowing chemists to construct substituted biaryl and related structures. This makes the material relevant to pharmaceutical intermediates, agrochemical research, specialty chemicals, and medicinal chemistry programs.

Use in Pharmaceutical Intermediate Manufacturing

Phenylboronic acid may be used at different stages of pharmaceutical intermediate synthesis, depending on the target molecule and route design. Its value is usually connected to synthetic flexibility rather than to a single finished-product application. For production use, I recommend confirming whether the supplier can provide consistent batch quality, traceability, suitable packaging, and documentation aligned with the buyer’s quality system.

Research and Analytical Applications

Researchers may also use phenylboronic acid in method development, reaction screening, and studies involving reversible boronate interactions. However, research use does not automatically mean that the material is suitable for regulated manufacturing. If the product will enter a validated or controlled process, I advise reviewing the supplier’s available certificate of analysis, lot information, test methods, and change-notification practices.

Types, Material Options, and Key Specifications

For most purchasing projects, the main material option is standard Phenylboronic acid CAS 98-80-6. The meaningful differences between offers are more likely to involve purity grade, test methods, packaging, batch size, and supply consistency than a fundamentally different chemical form. Some buyers may also request a customized specification based on reaction sensitivity or downstream impurity controls.

Specification Area What I Recommend Checking Why It Matters
Identity CAS number, chemical name, formula, and analytical identification Confirms that the quoted product matches the required substance
Assay and purity Reported assay value, method, and related substances Helps assess reaction performance and impurity control
Physical properties Appearance, solid form, and handling condition Supports receiving, weighing, and process preparation
Moisture and solvents Water content and residual solvent requirements where relevant May affect sensitive reactions and downstream processing
Packaging Container material, net weight, labeling, and sealing Protects the product and supports warehouse control

The molecular weight of Phenylboronic acid is 121.93 g/mol, which is useful for stoichiometric calculations and material planning. I also recommend checking whether the supplier’s certificate reports results on an as-is basis or another stated basis, because the interpretation of assay and moisture data depends on the reporting convention. Buyers should not assume that a general “high purity” description replaces a defined specification.

How to Match the Material to Your Application

Step 1: Define the Reaction or Process Requirement

I first ask what the material will do in the process. A laboratory screening project may prioritize small pack sizes and fast availability, while a manufacturing route may prioritize lot-to-lot consistency, impurity control, packaging, and long-term supply. The required specification should be based on demonstrated process sensitivity rather than on an unnecessarily broad list of tests.

Step 2: Establish the Quality Level

Next, I recommend defining the minimum acceptable assay, impurity limits, moisture range, and documentation package. If the customer has an internal standard, I compare the supplier’s routine specification with that standard before discussing price. Where a special limit is required, the buyer should confirm whether it is tested on every batch, tested periodically, or available only by request.

With competitive price and timely delivery, Maison Chemical sincerely hope to be your supplier and partner.

Step 3: Confirm Quantity and Packaging

Quantity affects packaging, production planning, shipping arrangements, and commercial terms. A buyer should provide the expected order quantity, forecast frequency, destination, and preferred pack size when requesting a quotation. For repeat supply, I also recommend discussing whether the same packaging configuration can be maintained across future batches.

Step 4: Review Documentation and Logistics

Before approval, I suggest reviewing the certificate of analysis, product specification, safety documentation, label information, and shipping requirements. Buyers should also confirm the proposed lead time, production location, export documentation, and any special transport or storage instructions. These details can have a greater effect on project risk than a small difference in unit price.

Pricing, MOQ, and Lead-Time Considerations

Phenylboronic acid pricing is influenced by order quantity, purity requirement, packaging, destination, testing scope, and market conditions. I do not recommend relying on a universal public price because a laboratory pack and a production order are not directly comparable. Instead, buyers should request a quotation based on a defined quantity and specification.

Minimum order quantity may differ by packaging format and whether the material is available from stock or scheduled for production. Lead time can also vary according to inventory status, quality release, export preparation, and shipping route. As a practical planning point, buyers should share their required delivery date at the quotation stage rather than assuming that a listed product is immediately available.

Supplier Evaluation Checklist

When I evaluate a supplier, I focus on evidence that can be reviewed and repeated. A credible supplier should be able to explain the product identity, routine specification, test documentation, packaging method, and order process without making unsupported absolute claims. I also look for clear communication about what is standard, what is customized, and what must be confirmed for each batch.

  • Can the supplier confirm CAS 98-80-6 and the requested chemical identity?
  • Does the quotation state assay, impurity, moisture, packaging, and documentation expectations?
  • Can the supplier provide a representative certificate of analysis or agreed batch documentation for review?
  • Are MOQ, lead time, delivery terms, and payment conditions clearly defined?
  • Can the supplier support repeat orders and communicate specification or packaging changes?
  • Does the supplier understand pharmaceutical intermediate and fine chemical purchasing requirements?

I also advise buyers to distinguish between manufacturing capability and trading availability. A supplier that can coordinate export supply may be suitable for one project, while a supplier with stronger production planning or customization support may be preferable for a long-term program. The best decision depends on the buyer’s risk tolerance, forecast accuracy, quality requirements, and delivery schedule.

Common Purchasing Mistakes

One common mistake is selecting the lowest quoted price before confirming whether all offers use the same assay basis, packaging, and test scope. Another is treating a catalog description as a complete technical specification. Buyers can also create avoidable delays by requesting a delivery date without providing the quantity, destination, documentation needs, or approval process.

I recommend avoiding unsupported assumptions about stability, regulatory suitability, or process performance. Phenylboronic acid should be stored and handled according to the supplier’s current safety and storage instructions, and every customer should evaluate compatibility with its own process conditions. If a sensitive application is involved, a small technical evaluation may be appropriate before committing to a larger commercial order.

How Maison Chemical Supports B2B Buyers

At Maison Chemical, I approach Phenylboronic acid CAS 98-80-6 as a specification and supply planning project, not only as a product listing. I can help organize discussions around intended use, required quality level, quantity, packaging, documentation, and delivery destination. This allows the quotation to reflect the buyer’s actual requirements more accurately.

For pharmaceutical intermediate and fine chemical customers, I can also support communication between procurement, quality, logistics, and technical teams. Depending on the order and confirmed product requirements, the supply discussion may include batch documentation, export paperwork, packaging options, and repeat-order planning. All details should be confirmed in the commercial and technical documentation before purchase.

Key Takeaways for Buyers

  • Phenylboronic acid CAS 98-80-6 is commonly used in organic synthesis, particularly Suzuki–Miyaura coupling and intermediate manufacturing.
  • The confirmed molecular formula is C6H7BO2, and the molecular weight is 121.93 g/mol.
  • CAS identity alone is not enough; buyers should review assay, impurities, moisture, packaging, documentation, and supply terms.
  • Price, MOQ, and lead time should be evaluated against the same specification and delivery conditions.
  • A reliable supplier should provide clear, reviewable information and realistic commitments for the intended order.

Conclusion: Choosing the Right Phenylboronic Acid Supplier

The right Phenylboronic acid CAS 98-80-6 supplier is the one that can meet your defined technical specification, quantity, documentation, and delivery requirements with clear communication. I recommend starting with your application, then confirming the quality level, packaging, forecast, and approval documents before comparing quotations. This process gives you a more meaningful basis for evaluating total sourcing risk.

If you are planning to purchase Phenylboronic acid for research, pharmaceutical intermediate production, or fine chemical manufacturing, Maison Chemical can review your requirements and prepare a suitable B2B supply discussion. Please provide the desired quantity, purity or specification, packaging preference, destination, and target delivery schedule so I can help determine the next practical step.

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