I use this guide to help research, procurement, and process-development teams evaluate 3,5-Dichlorophenylboronic acid, CAS 67492-50-6, before requesting a quotation. The compound is an aryl boronic acid used primarily as a synthetic building block, especially in palladium-catalyzed carbon–carbon coupling chemistry. Its molecular formula is commonly represented as C6H5BCl2O2, with a calculated molecular weight of approximately 190.82 g/mol. Buyers should confirm the supplier’s current specification, analytical data, packaging, and delivery conditions because product requirements can vary by application and project stage.
This guide is intended for pharmaceutical and agrochemical researchers, contract development and manufacturing organizations, chemical distributors, university laboratories, and industrial procurement teams. It is particularly relevant when a project requires a halogenated aromatic boronic acid for laboratory synthesis, route scouting, process development, or intermediate manufacturing. I recommend using the information below as a technical screening framework rather than as a substitute for the supplier’s certificate of analysis or safety documentation.
3,5-Dichlorophenylboronic acid is an aromatic boronic acid containing a phenyl ring substituted with chlorine atoms at the 3- and 5-positions and a boronic acid group at the 1-position. The boronic acid functionality can participate in cross-coupling reactions, while the two chlorine substituents remain part of the aromatic structure and may influence the electronic and steric behavior of the intermediate. This combination makes the compound useful when a synthesis requires both a transferable aryl group and a dichlorinated aromatic framework.
In practical purchasing terms, CAS 67492-50-6 identifies the chemical substance, but it does not by itself define purity, particle size, packaging, residual solvents, or manufacturing scale. I therefore treat the CAS number as the starting point for identity confirmation, not as a complete product specification. A quotation should be reviewed together with the product name, molecular formula, molecular weight, purity method, and batch-specific documentation.
The most important specifications are identity, assay or purity, water content, residual solvents, inorganic residues, and physical description. For early-stage research, a standard analytical grade may be sufficient, while regulated or scale-up work can require tighter impurity control and documented analytical methods. If the supplier does not publish a fixed value for a parameter, I recommend requesting confirmation before placing the order rather than assuming that an industry-standard limit applies.
| Specification Area | What to Confirm | Why It Matters |
|---|---|---|
| Identity | CAS 67492-50-6, structure, formula, and analytical identification | Reduces the risk of selecting a positional isomer or incorrectly labeled material |
| Purity | Assay method, stated purity level, and known related substances | Supports reaction reproducibility and impurity assessment |
| Water and solvents | Water content and residual solvent limits where relevant | Helps control moisture-sensitive or solvent-sensitive processes |
| Documentation | COA, SDS, batch or lot traceability, and packaging information | Supports internal quality review and receiving inspection |
Because boronic acids can show behavior affected by moisture, storage history, and analytical method, I advise buyers to compare like with like. A reported HPLC purity, for example, should not automatically be treated as equivalent to a specification based on another method. For a new supplier, I would request a representative COA, analytical method details, and a small evaluation quantity before committing to a larger commercial order.
The principal application is as an aryl component in Suzuki–Miyaura and related cross-coupling reactions. In a suitable reaction system, the boronic acid group can provide the aryl fragment needed to form a carbon–carbon bond with an appropriate aryl or heteroaryl halide. Researchers should optimize catalyst, base, solvent, temperature, concentration, and reaction time for the specific substrate combination rather than assuming that one literature procedure will transfer directly.
The 3,5-dichloro substitution pattern can be valuable in medicinal chemistry programs that require a defined halogenated aromatic motif. It may also serve as an intermediate for preparing analogues during structure–activity relationship studies. I would still recommend confirming the compatibility of the chlorine substituents with the selected reaction conditions, particularly when strong bases, elevated temperatures, or multifunctional coupling partners are involved.
In agrochemical research, this compound may be considered when a development route needs a dichlorinated aryl building block. In materials or specialty chemical research, it may support the preparation of functional aromatic intermediates or screening compounds. These uses should be described as potential synthetic applications unless a specific validated route, product registration, or application record has been established for the buyer’s project.
For most buyers, the meaningful “material options” are not different chemical grades of the same name but differences in purity target, pack size, documentation, and production scale. A research team may need a small package for route screening, whereas a process team may require a larger quantity with tighter lot consistency and advance production planning. I recommend specifying whether the request is for laboratory evaluation, pilot work, or routine commercial supply.
Maison Chemical can discuss standard supply and project-based requirements for 3,5-Dichlorophenylboronic acid CAS 67492-50-6. Depending on the project, the commercial discussion may include package size, export packing, labeling, documentation, sample availability, and repeat-order planning. Final availability, MOQ, and lead time should be confirmed in a written quotation because they can depend on inventory, production scheduling, order volume, and destination requirements.
First, I identify whether the material is intended for reaction screening, analytical reference work, process development, or commercial intermediate production. The intended use determines the appropriate purity target, documentation level, package size, and amount of material needed. It also prevents a buyer from paying for requirements that are unnecessary at an early discovery stage or overlooking controls needed for scale-up.
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Next, I compare the supplier’s product identity against CAS 67492-50-6, the expected structure, formula, and approximate molecular weight of 190.82 g/mol. I then request the applicable COA and ask how purity is measured. If the project has a controlled impurity profile, I provide the supplier with the relevant limits before quotation so that feasibility can be assessed accurately.
I also check whether the proposed packaging protects the material from unsuitable exposure during storage and transport. The SDS should be reviewed for hazard classification, handling precautions, recommended storage, and transport information. Buyers should follow the supplier’s current SDS rather than relying on generic assumptions about the physical or chemical hazards of boronic acids.
Finally, I assess whether the supplier can support repeat orders, consistent documentation, and communication across the project lifecycle. A low initial price may not represent the lowest total procurement risk if the supplier cannot confirm lot traceability or future availability. For an important intermediate, I prefer to discuss a sample, a qualification order, and a realistic forecast before requesting long-term supply commitments.
One common mistake is selecting material based only on the CAS number and product title. Another is comparing prices without checking purity basis, packaging, shipping terms, analytical documentation, or whether the quoted quantity is actually available. Buyers may also assume that a reaction optimized with another aryl boronic acid will perform identically with the 3,5-dichloro analogue.
A further mistake is requesting “high purity” without defining the analytical method or acceptance criteria. I obtain better quotations when I state the target quantity, intended application, required documents, destination country, and preferred delivery window. This information enables the supplier to distinguish a routine stock inquiry from a qualification or scale-up requirement.
Pricing for 3,5-Dichlorophenylboronic acid can vary according to quantity, purity requirement, packaging, manufacturing route, inventory status, and destination. I do not recommend publishing a fixed price without confirming these variables because a laboratory pack and a larger production quantity may have different cost structures. The most useful quotation should clearly state unit price, quantity basis, MOQ, Incoterms where applicable, packaging, payment terms, and validity period.
Lead time should likewise be confirmed for each order rather than inferred from a general product listing. Stock material may follow a different schedule from made-to-order material, and export documentation can affect dispatch timing. For time-sensitive programs, I suggest requesting a written availability statement and discussing whether a forecast or scheduled release plan is appropriate.
As a supplier of organic boronic acids, Maison Chemical supports B2B buyers by organizing product information around identity, specifications, documentation, packaging, and supply planning. I can help clarify the intended grade, quantity, and documentation package before a quotation is prepared. Where a requirement is not covered by a standard specification, I recommend discussing it early so that the request can be evaluated realistically rather than treated as an automatic commitment.
For an initial inquiry, I suggest sending CAS 67492-50-6, target quantity, required purity, application stage, destination, preferred pack size, and desired delivery window. If available, include the buyer’s internal specification or COA requirements. This creates a more efficient technical and commercial review and helps identify whether a sample, standard batch, or planned production order is the best next step.
For buyers asking whether 3,5-Dichlorophenylboronic acid CAS 67492-50-6 is suitable for their project, the answer depends on the required coupling route, purity profile, documentation, quantity, and supply schedule. Its defined dichlorophenyl structure and boronic acid functionality make it a relevant building block for medicinal chemistry, agrochemical research, and other synthetic programs, but application performance must be verified experimentally. The safest purchasing decision combines chemical identity confirmation with batch-specific quality and commercial review.
To begin, contact Maison Chemical with your target quantity, purity requirement, application stage, destination, and documentation expectations. I can then help assess the appropriate supply format, confirm current availability, and prepare a quotation for evaluation or repeat procurement. This structured approach gives your team a clearer basis for supplier comparison and a more reliable path from laboratory screening to planned supply.
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